I have tried it with VMWare and it works great, don't get me started on Parallels. We use only Mac's and I have to use Windows to run UPS Worldship everyday, it uses a lot of memory, especially with our Filemaker program running in the background. Parallels crashed almost weekly, never updated properly and we had to reconfigure the USB peripheral settings daily. When you get to your wits end, try VMWare, it is faster, smaller and very trouble free. I could never see going back. I think it should work fine, but I can't stand Parallels and couldn't justify buying the upgrade from 3.0, to 4.0 so we switched and it was the best choice we could have made.