Mark's 180 Starfire upgrade

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Mark, out of curiosity, what is the suggested benefit of the praziquantril (prazipro?). I thought it was only good for treating fish worms and flukes? {shows what I know}
 
<a href=showthread.php?s=&postid=13417886#post13417886 target=_blank>Originally posted</a> by petes97
Mark, out of curiosity, what is the suggested benefit of the praziquantril (prazipro?). I thought it was only good for treating fish worms and flukes? {shows what I know}

It does say right on the bottle that it works of flatworms. I have heard varied reports, but I believe more in 1st hand experience than rumors around the water cooler.

I will be posting my different experiences along the way, believe you me ;)
 
mark, sounds like you've got the tools and are ready for battle! i'm available after 2pm saturday if you want help.

sps systems are so up/down all the time :mad2:. so many variables that could go wrong. if it were easy, everyone with a sps tank started from frags would have 12" colonies after 2-3 years :(.
 
Mark goodluck on your move this saturday. Hope all goes well and as you can see people comments are making you stronger everyday :)
 
<a href=showthread.php?s=&postid=13418452#post13418452 target=_blank>Originally posted</a> by tfp
mark, sounds like you've got the tools and are ready for battle! i'm available after 2pm saturday if you want help.

sps systems are so up/down all the time :mad2:. so many variables that could go wrong. if it were easy, everyone with a sps tank started from frags would have 12" colonies after 2-3 years :(.

Thanks Tim, I could use an experienced set of hands and eyes for a couple hours that Amanda and Emma are familiar with.

You are definitely right about SPS tanks. "If its not one thing, its another" That is just another example of how special your tank is. ;)
 
<a href=showthread.php?s=&postid=13418052#post13418052 target=_blank>Originally posted</a> by mpoletti
It does say right on the bottle that it works of flatworms. I have heard varied reports, but I believe more in 1st hand experience than rumors around the water cooler.

I will be posting my different experiences along the way, believe you me ;)

Mark, actually I was going to PM but I forgot (my dental exam is coming up)

I've looked up a LOTS of research papers and an antihelminthic drug that came up was praziquantel (I'm wondering if it's close to prazipro) . I've seen this drug used on FW fish with worm infestation. I wanted to conduct an experiment on my own prior standing behind it but I haven't found the time.

There's my update. Hope everything is well.

Jay
 
<a href=showthread.php?s=&postid=13421215#post13421215 target=_blank>Originally posted</a> by eagleONE
Mark, actually I was going to PM but I forgot (my dental exam is coming up)

Jay

Good luck ;)
 
Mark
How come you are going to use prazipro instead of straight praziquantrel?

I have used straight praziquantrel on my fish before that had worms and it worked awesome.

I have also seen it kill bristle worms to.


Chris
 
<a href=showthread.php?s=&postid=13423178#post13423178 target=_blank>Originally posted</a> by reefer334
Mark
How come you are going to use prazipro instead of straight praziquantrel?

It comes down to access and recommendations. I have having a hard time even thinking of using a new product on a colony of Pink Lemonade, Purple Monster, Paletta Pink Tip or any of the other corals that I know have a pretty decent market value. :(
 
<a href=showthread.php?s=&postid=13423178#post13423178 target=_blank>Originally posted</a> by reefer334
Mark
How come you are going to use prazipro instead of straight praziquantrel?

I have used straight praziquantrel on my fish before that had worms and it worked awesome.

I have also seen it kill bristle worms to.


Chris

A month or so ago I did a search of all AEFW threads and read thru just about all of them. Sadly most seem to have just died out a long time ago (2006). There was some promising research being done by a few RC members. This was one of the best threads I found:

http://www.reefcentral.com/forums/showthread.php?s=&threadid=858834&perpage=25&pagenumber=3

Dolt was onto some good stuff:

<a href=showthread.php?s=&postid=7538120#post7538120 target=_blank>Originally posted</a> by dolt
OK - I started wondering what medicine would make the most sense to use - to do this I began to review some worm phylogeny - Platyhelminthes (flat worms) are divided into three groups - planaria (this includes ones that live in ocean and freshwater environments - eg our AEFW), trematodes (flukes), and cestodes (tapeworms) - according to a UC Berkely website I found planaria and trematodes seem to share a common ancestor - we therefore need to focus on medications that will selectively treat trematodes in humans or other animals (as far as I am aware there are no serious human parasitic planarians) - human tapeworms are cestodes and may not be as closely related to the AEFW and therefore meds that work on them may not work as well on AEFW as ones for trematodes - the funny thing is that this may all be moot as praziquantel is proven to be effective against trematode and cestode infections in humans - in fact praziquantel is so effective in humans that basically no other medicines are readily available for treatment of trematode infections (as above, nicloside is a second choice in other parts of the world, but is no longer available in the US)

SeatT also had a good thread going:

http://www.reefcentral.com/forums/showthread.php?s=&threadid=688833&highlight=AEFW


If my memory serves me correctly, I believe Prazi Pro was found to be ineffective. I believe the issue was around sufficient solubility or lack there of. I don't have the patience to read back thru all these threads again to find the specific research but maybe someone else does :) Praziquentel is the active ingredient and pure prazi is quite soluble. I located it locally at Connie's Pond Store in San Leandro. It is expensive but if it works, way cheaper than replacing rare acros.

My personal feeling is that, like Red Bugs, dipping treatments will be futile in ridding the entire tank. The cure will lie in a full tank treatment and Praziquentel seems to be the most promising drug right now.

As for worrying a lot about eggs, it will be mute in a full tank treatment as a treatment regimen will take into account the full life cycle of the parasite (Just like Interceptor treatment of Red Bugs).

Hope this help stimulate some fresh conversation and creative thinking.
 
Thanks Erik, I have about 10 different links to some of the older threads that are now in the archives here on RC.

I have also heard from a few people here on RC and on some other boards, that they have had some good results with Prazipro. But I also have heard about good results with fluke tabs and we don't need to go there :(

I did find it in a "purer" concentration, but after speaking to a few people that have have decent results, I just went the easy route as I needed a new wet side for a vortech as well. I probably will not even use it on this round of dipping.

I agree about the "in tank treatment" and that is why I will be removing all of my acroporas and about 1/3 of the Live rock. I plan on breaking the life cycle by leaving the tank acroless for a period of time. The key will be cutting off all bases and inspecting closely, before putting any of the corals back in display.

I definitely understand that there are risks involved in this, but as you know me, I can not be happy knowing that they are in my tank. My Nikon has been getting no action and there are some days that I just turn off the lights rather to look at the tank.

If I am going to stay in this hobby, I will need to overcome these buggers or at least go out swinging.
 
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But I also have heard about good results with fluke tabs and we don't need to go there

Teach me about this Mark cus I have never used anything other then fluke tabs for AEFW since starting my 700 and if they didn't work I would have them all over my tank, my corals came from a 450g infected with flatworms-help me understand
 
Joe, Erik lost his coral collection in a transfer while using fluke tabs. I have heard plenty of good things as well. I think it is up to the individual as I know a lot of people that have had a lot of bad luck with levamisole and I think its just fine. One thing about a lot of reefers is that is if the directions say one thing, they always think more is better :)
 
Not sure what Erik did, but if you would like to send me a few choice infected corals I can add to my system, I will fluke them too with no worries-seriously
 
Mark, now that I look back at one of the PM I received about Prazi Pro. It seems that the one of the peolpe I talked with never mentioned Prazi Pro, but rather prazi. I have talked to him since and he was refering to Praziquentel. His is
made by Hikari. It seems to make since, from all the breed I have talk to Prazi Pro seems to be not very solubility. Alot of them compained about foaming when using it to treat fish.
 
I think the one I ordered was made by Hikari as well. Oh well :( Its going to be a levamisole dip the first time around anyways.
 
Mark
You can get praziquantrel here

http://www.1800petmeds.com/Tape+Worm+Tabs+Cat-prod10415.html

I have used on my cats it is just a general dewormer.
This is the stuff I used on my fish with awesome results,
and yes I know what you mean by the high end corals that would make me nervous to, but I used mine one some very expensive fish with good results.


I hope it goes well for you.

Have you thought about braking off a frag that has AEFW on it and experimenting that way with praziquantrel?

that way you would not put the whole colony at risk.

Have you talked to any vets or people at UC Davis?

Chris
 
Yes Chris, I have spoke to various vets, marine biologist, advanced marine aquarists and polyclad experts.

I will be experimenting with some of the corals that I am "less attached" to. At this point, it is what it is and it will end up however it ends up ;)
 
Mark
I hope it works out for you, I am preying to the coral gods for you.

Your tank has been inspiration for me to keep going in this hobby even when I to just want to give up.

If you ever need any help just LMK I am just down the road from you.

Chris
 
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